Understanding a patient’s diagnosis
In this section you can find an infographic providing an overview of the diagnostic pathway in aTTP, and expert interviews discussing the challenges in diagnosing TTP.
TTP Diagnostic pathway
The diagnosis of TTP should be treated as a medical emergency.1 Thrombocytopaenia & MAHA in the absence of any other identifiable cause => suspect TTP.1
Presenting clinical features and signs include1:
Potential triggers of interest in clinical history2:
Tests and expected results may include1:
Blood samples should be sent for investigation before first PEX1
Blood must be taken prior to treatment to assess baseline ADAMTS13 activity.
Severely reduced ADAMTS13 activity helps to confirm the diagnosis of TTP1
- Scully M et al. Br J Haematol 2012;158:323–335.
- Veyradier A, Meyer D. J Thromb Haemost 2005;3:2420–7.